CogniAid™ | Stuðningur við minni, einbeitingu og hugræna virkni
CogniAid™ | Stuðningur við minni, einbeitingu og hugræna virkni
ÍTARLEGRI UPPLÝSINGAR
Taktu 2 hylki á dag með máltíðum eða samkvæmt leiðbeiningum heilbrigðisstarfsmanns.
1. Xu ZQ, Liang XM, Juan-Wu, Zhang YF, Zhu CX, Jiang XJ. Treatment with huperzine A improves cognition in vascular dementia patients. Cell Biochem Biophys. 2012;62(1):55-58. doi:10.1007/s12013-011-9258-5.
2. Ha GT, Wong RK, Zhang Y. Huperzine a as potential treatment of Alzheimer’s disease: an assessment on chemistry, pharmacology, and clinical studies. Chem Biodivers. 2011;8(7):1189-1204. doi:10.1002/cbdv.201000269.
3. Zheng W, Xiang YQ, Li XB, et al. Adjunctive huperzine A for cognitive deficits in schizophrenia: a systematic review and meta-analysis. Hum Psychopharmacol. 2016;31(4):286-295. doi:10.1002/hup.2537.
4. Ratia M, Giménez-Llort L, Camps P, et al. Huprine X and huperzine A improve cognition and regulate some neurochemical processes related with Alzheimer’s disease in triple transgenic mice (3xTg-AD). Neurodegener Dis. 2013;11(3):129-140. doi:10.1159/000336427.
5. Gul A, Bakht J, Mehmood F. Huperzine-A response to cognitive impairment and task switching deficits in patients with Alzheimer’s disease. J Chin Med Assoc. 2019;82(1):40-43. doi:10.1016/j.jcma.2018.07.004.
6. Cai Y, Huang P, Xie Y. Effects of huperzine A on hippocampal inflammatory response and neurotrophic factors in aged rats after anesthesia. Acta Cir Bras. 2020;34(12):e201901205. doi:10.1590/s0102-865020190120000005.
7. Yang G, Wang Y, Tian J, Liu JP. Huperzine A for Alzheimer’s disease: a systematic review and meta-analysis of randomized clinical trials. PLoS One. 2013;8(9):e74916. doi:10.1371/journal.pone.0074916.
8. Sukumaran NP, Amalraj A, Gopi S. Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst – a review on its mechanistic aspects. Complement Ther Med. 2019;44:68-82. doi:10.1016/j.ctim.2019.03.016.
9. Kean JD, Downey LA, Stough C. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations. Complement Ther Med. 2016;29:56-62. doi:10.1016/j.ctim.2016.09.002.
10. Aguiar S, Borowski T. Neuropharmacological review of the nootropic herb Bacopa monnieri. Rejuvenation Res. 2013;16(4):313-326. doi:10.1089/rej.2013.1431.
11. Benson S, Downey LA, Stough C, Wetherell M, Zangara A, Scholey A. An acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and mood. Phytother Res. 2014;28(4):551-559. doi:10.1002/ptr.5029.
12. Abdul Manap AS, Vijayabalan S, Madhavan P, et al. Bacopa monnieri, a neuroprotective lead in alzheimer disease: a review on its properties, mechanisms of action, and preclinical and clinical studies. Drug Target Insights. 2019;13:1177392819866412. doi:10.1177/1177392819866412.
13. Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, Limpeanchob N, Norman Scholfield C. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol. 2014;151(1):528-535. doi:10.1016/j.jep.2013.11.008.
14. Downey LA, Kean J, Nemeh F, et al. An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance. Phytother Res. 2013;27(9):1407-1413. doi:10.1002/ptr.4864.
15. Pase MP, Kean J, Sarris J, Neale C, Scholey AB, Stough C. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. J Altern Complement Med. 2012;18(7):647-652. doi:10.1089/acm.2011.0367.
16. Ma L, Sun Z, Zeng Y, Luo M, Yang J. Molecular mechanism and health role of functional ingredients in blueberry for chronic disease in human beings. Int J Mol Sci. 2018;19(9):2785. doi:10.3390/ijms19092785.
17. Lamport DJ, Lawton CL, Merat N, et al. Concord grape juice, cognitive function, and driving performance: a 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children. Am J Clin Nutr. 2016;103(3):775-783. doi:10.3945/ajcn.115.114553.
18. Tan L, Yang HP, Pang W, et al. Cyanidin-3-O-galactoside and blueberry extracts supplementation improves spatial memory and regulates hippocampal ERK expression in senescence-accelerated mice. Biomed Environ Sci. 2014;27(3):186-196. doi:10.3967/bes2014.007.
19. Mohan S, Gobinath T, Salomy A, et al. Biophysical interaction of resveratrol with sirtuin pathway: significance in Alzheimer’s disease. Front Biosci (Landmark Ed). 2018;23:1380-1390. doi:10.2741/4650.
20. Hein S, Whyte AR, Wood E, Rodriguez-Mateos A, Williams CM. Systematic review of the effects of blueberry on cognitive performance as we age. J Gerontol A Biol Sci Med Sci. 2019;74(7):984-995. doi:10.1093/gerona/glz082.
21. Krikorian R, Boespflug EL, Fleck DE, et al. Concord grape juice supplementation and neurocognitive function in human aging. J Agric Food Chem. 2012;60(23):5736-5742. doi:10.1021/jf300277g.
22. Boespflug EL, Eliassen JC, Dudley JA, et al. Enhanced neural activation with blueberry supplementation in mild cognitive impairment. Nutr Neurosci. 2018;21(4):297-305. doi:10.1080/1028415X.2017.1287833.
23. McNamara RK, Kalt W, Shidler MD, et al. Cognitive response to fish oil, blueberry, and combined supplementation in older adults with subjective cognitive impairment. Neurobiol Aging. 2018;64:147-156. doi:10.1016/j.neurobiolaging.2017.12.003.
24. Miller MG, Hamilton DA, Joseph JA, Shukitt-Hale B. Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial. Eur J Nutr. 2018;57(3):1169-1180. doi:10.1007/s00394-017-1400-8.
25. Devore EE, Kang JH, Breteler MM, Grodstein F. Dietary intakes of berries and flavonoids in relation to cognitive decline. Ann Neurol. 2012;72(1):135-143. doi:10.1002/ana.23594.
26. Whyte AR, Cheng N, Butler LT, Lamport DJ, Williams CM. Flavonoid-rich mixed berries maintain and improve cognitive function over a 6 h period in young healthy adults. Nutrients. 2019;11(11):2685. doi:10.3390/nu11112685.
27. Bowtell JL, Aboo-Bakkar Z, Conway ME, Adlam AR, Fulford J. Enhanced task-related brain activation and resting perfusion in healthy older adults after chronic blueberry supplementation. Appl Physiol Nutr Metab. 2017;42(7):773-779. doi:10.1139/apnm-2016-0550.
28. Lee J, Torosyan N, Silverman DH. Examining the impact of grape consumption on brain metabolism and cognitive function in patients with mild decline in cognition: a double-blinded placebo controlled pilot study. Exp Gerontol. 2017;87(pt A):121-128. doi:10.1016/j.exger.2016.10.004.
29. Bensalem J, Dudonné S, Etchamendy N, et al. Polyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: a bicentric double-blind, randomized, placebo-controlled clinical study. J Gerontol A Biol Sci Med Sci. 2019;74(7):996-1007. doi:10.1093/gerona/gly166.
30. Barfoot KL, May G, Lamport DJ, Ricketts J, Riddell PM, Williams CM. The effects of acute wild blueberry supplementation on the cognition of 7-10-year-old schoolchildren. Eur J Nutr. 2019;58(7):2911-2920. doi:10.1007/s00394-018-1843-6.
31. Haskell-Ramsay CF, Stuart RC, Okello EJ, Watson AW. Cognitive and mood improvements following acute supplementation with purple grape juice in healthy young adults [published correction appears in Eur J Nutr. October 6, 2017]. Eur J Nutr. 2017;56(8):2621-2631. doi:10.1007/s00394-017-1454-7.
32. Choudhary D, Bhattacharyya S, Bose S. Efficacy and safety of ashwagandha (Withania somnifera (L.) dunal) root extract in improving memory and cognitive functions. J Diet Suppl. 2017;14(6):599-612. doi:10.1080/19390211.2017.1284970.
33. Dar NJ, MuzamilAhmad. Neurodegenerative diseases and Withania somnifera (L.): an update. J Ethnopharmacol. 2020;256:112769. doi:10.1016/j.jep.2020.112769.
34. Pandey A, Bani S, Dutt P, Kumar Satti N, Avtar Suri K, Nabi Qazi G. Multifunctional neuroprotective effect of Withanone, a compound from Withania somnifera roots in alleviating cognitive dysfunction. Cytokine. 2018;102:211-221. doi:10.1016/j.cyto.2017.10.019.
35. Ng QX, Loke W, Foo NX, et al. A systematic review of the clinical use of Withania somnifera (Ashwagandha) to ameliorate cognitive dysfunction. Phytother Res. 2020;34(3):583-590. doi:10.1002/ptr.6552.
36. Chengappa KN, Bowie CR, Schlicht PJ, Fleet D, Brar JS, Jindal R. Randomized placebo-controlled adjunctive study of an extract of withania somnifera for cognitive dysfunction in bipolar disorder. J Clin Psychiatry. 2013;74(11):1076-1083. doi:10.4088/JCP.13m08413.
37. Szczuka D, Nowak A, Zakłos-Szyda M, et al. American ginseng (Panax quinquefolium L.) as a source of bioactive phytochemicals with pro-health properties. Nutrients. 2019;11(5):1041. doi:10.3390/nu11051041.
38. Qi LW, Wang CZ, Yuan CS. Ginsenosides from American ginseng: chemical and pharmacological diversity. Phytochemistry. 2011;72(8):689-699. doi:10.1016/j.phytochem.2011.02.012.
39. Shin K, Guo H, Cha Y, et al. Cereboost™, an American ginseng extract, improves cognitive function via up-regulation of choline acetyltransferase expression and neuroprotection. Regul Toxicol Pharmacol. 2016;78:53-58. doi:10.1016/j.yrtph.2016.04.006.
40. Chen EY, Hui CL. HT1001, a proprietary North American ginseng extract, improves working memory in schizophrenia: a double-blind, placebo-controlled study. Phytother Res. 2012;26(8):1166-1172. doi:10.1002/ptr.3700.
41. Scholey A, Ossoukhova A, Owen L, et al. Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study. Psychopharmacology (Berl). 2010;212(3):345-356. doi:10.1007/s00213-010-1964-y.
42. Ossoukhova A, Owen L, Savage K, et al. Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults. Hum Psychopharmacol. 2015;30(2):108-122. doi:10.1002/hup.2463.
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